The best of 2 worlds – medical competence meets AI

Visual
findings

Accurate
measurement results

The software AIRAscore structure uses current procedures of artificial intelligence (AI) and measures the brain volume and changes thereof based on MR-images of the head.

The result is an evaluation report with precisely measured values of various brain structures that are important for diagnostics.

Early diagnosis, better and more reliable differential diagnoses as well as individual therapies are thus made easier – or even possible in the first place.

These objective measurement and comparative values can be considered as second opinion by your physician, and can thus be incorporated in his diagnosis.

Early, as well as better and more reliable differential diagnoses, and individual therapies are thus simplified.

Changes in the brain – normal or pathological?

The human brain consists of the so-called gray matter (the nerve cells), the white matter (the connecting fibres) and is surrounded by cerebrospinal fluid (the brain fluid). The individual brain regions have different volumes. They can change, for example, as part of the normal ageing process.

But they also change when certain neurodegenerative diseases are present or developing and progressing. Depending on which regions of the brain are affected, changes in brain volume indicate different pathologies.

Well-known neurodegenerative diseases include dementia with its subtypes, such as Alzheimer’s disease, but also pathologies such as multiple sclerosis or Parkinson’s disease.

Healthy
brain

Diseased
brain

This is why precise measurement methods are so important for diagnostics

For optimized early detection, because...

changes in brain volume can only be detected at an advanced stage by visual examination. This means that valuable time often elapses before the initial diagnosis is made or during follow-up examinations.

As a supplement to purely visual findings, because...

radiologists currently rely on the naked eye to decide whether and to what extent abnormalities are present. To do this, they view hundreds of images per patient on average. Therefore, regarding a single image, the radiologist only spends seconds.

For objective reference values,
because …

your doctor usually does not have access to objective reference values for a conventional diagnosis. Interpretations, diagnoses and treatment recommendations are therefore strongly dependent on the doctor’s experience and often differ, even amongst experts.

For a reliable assessment of abnormalities, because …

ambiguous interpretations make it difficult to assign them to known pathologies or, in medical terms, to make a differential diagnosis.

More options for diagnostic findings – highlights of our evaluation report

Protection of your data

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Comparison with reference values
for increased reliability

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Measurement of important brain regions
for a better differential diagnosis

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Representation in traffic light form for quick comprehension

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The technology behind it explained in simple terms

 

 

MRI images of your brain

Suitable MRI image data are the basis of every evaluation.

They show layers of your brain – several hundred at intervals of about 1 mm. You can imagine this roughly like a flip book.

On each sheet you can see a frame of the ‘film’, but only the sequence results in the actual cinema film. Or in this case – a complete brain.

 

 

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Breakdown into voxels

At the beginning of the analysis, each of these layers is divided into a grid of cubes –
so-called voxels.

Each voxel is about 1 mm³ in size; for example, one voxel of the cerebral cortex contains about 90,000 nerve cells! This also explains why even small changes in volume are so important for a diagnosis!

 

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Segmentation and measurement

The software assigns the voxels to the individual brain structures. This is called segmentation.

The volume of the individual segments is then determined on the basis of this assignment.

 

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Comparison with healthy reference values

Taking into account individual parameters such as gender, age and head size, we check whether your measurement results are within the normal range.

Depending on whether there are deviations – also to what extent and within which structures – your doctor will have important indications of a disease.

We provide all evaluation results in a clear report. Accurate follow-up examinations are thus easily possible.

 

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An excerpt of our references

‘Especially in the case of rare neurological diseases, we are often faced with the problem of whether an individual brain scan is already conspicuous or not. AIRAscore provides great help in our daily work.’

Prof. Dr. Ludger Schöls
Neurologist, University Hospital of Tübingen, Germany

‘With AIRAscore structure, I can support my diagnosis and diagnose changes in brain volume that I would only have been able to detect much later with a purely visual assessment. This added value pleases my patients, but also me as a doctor.’

Dr. Sören Danz
Radiologist, Sindelfingen, Germany

‘I am pleased to be able to offer my patients the additional service provided by AIRAscore. Experience shows that very many patients are afraid of dementia in old age. AIRAscore helps me to distinguish healthy from sick aging and I recognize much earlier than with the pure visual findings whether and when concrete action is needed.’

Dr. Nicola Meyer
Radiologist, Hamburg, Germany

‘I am pleased that with AIRAscore structure we now have a way to benefit from the latest scientific findings in our private practice. It only takes a few minutes until I have exact measurement values directly in my PACS, which significantly improve my reporting options.’

PD Dr. Hansjörg Rempp
Radiologist, Stuttgart, Germany

‘We now use AIRAscore structure routinely with our inpatients. The findings report gives us the necessary security here in the assessment of dementia-related diseases.’

Prof. Dr. Gerhard Eschweiler
Psychiatrist, University Hospital of Tübingen, Germany

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